Views of parents of children with Down syndrome on Alzheimer’s disease vaccination

Individuals with Down syndrome (DS) experience increased risk of Alzheimer’s disease (AD). Recent studies suggest that a vaccine against AD may be forthcoming. Parental buy-in is critical to the success of any intervention in this population, as adults with DS often rely on familial support. This st...

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Veröffentlicht in:Journal of intellectual disabilities 2024-09, Vol.28 (3), p.759-772
Hauptverfasser: Batbold, Sarah, Cummings, Gabrielle, Riggan, Kirsten A., Michie, Marsha, Allyse, Megan
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Sprache:eng
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Zusammenfassung:Individuals with Down syndrome (DS) experience increased risk of Alzheimer’s disease (AD). Recent studies suggest that a vaccine against AD may be forthcoming. Parental buy-in is critical to the success of any intervention in this population, as adults with DS often rely on familial support. This study aims to characterize parents’ perceptions of a hypothetical vaccine to prevent AD in individuals with DS. A mixed-methods, anonymous survey was distributed via social media. Participants were asked about their experiences with DS and reactions to proposed interventions. Open-ended responses were thematically analyzed using NVivo 12. Of 1,093 surveys initiated, 532 were completed. Of the parents sampled (N = 532), a small majority (54.3%), supported the proposed AD vaccine. All expressed the need for extensive pre-enrollment education and minimal risk. For many, limited research and long-term sequelae were concerns.
ISSN:1744-6295
1744-6309
1744-6309
DOI:10.1177/17446295231177787