Predictors of antepartum maternal sepsis and effects on neonatal outcomes: a population-based cohort study

Objective To examine the relationship between maternal sepsis, type of infection, and short-term neonatal outcomes. Study design We conducted a retrospective cohort study investigating pregnancies between 2005 and 2008 in California with antepartum maternal sepsis diagnosis. Comparisons were made between sepsis cases and controls, using chi-squared or Fisher’s exact test. Multivariable logistic regression was performed, adjusting for maternal characteristics. Results Several maternal characteristics were associated with increased odds of maternal sepsis. Both obstetric and non-obstetric infections were associated with maternal sepsis ( p