Plasma amyloid-β biomarkers are associated with Alzheimer's disease comorbidity in Lewy body disease

Plasma amyloid-β biomarkers are associated with Alzheimer's disease comorbidity in Lewy body disease

No blood biomarkers which can identify Alzheimer's disease pathology in Lewy body disease (LBD) have ever been established. We showed that the plasma amyloid-β (Aβ) 1-42/Aβ1-40 ratio was significantly decreased in patients with Aβ+ LBD compared with those with Aβ- LBD and it might be a useful b...

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Veröffentlicht in:Parkinsonism & related disorders 2023-06, Vol.111, p.105445-105445, Article 105445
Hauptverfasser: Noguchi-Shinohara, Moeko, Murakami, Hidetomo, Sakashita, Yasuhiro, Mori, Yukiko, Komatsu, Junji, Muramatsu, Daiki, Hikishima, Sadao, Ono, Kenjiro
Format: Artikel
Sprache:eng
Schlagworte:
Alzheimer pathology
Lewy body disease
Plasma amyloid-β
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Zusammenfassung:No blood biomarkers which can identify Alzheimer's disease pathology in Lewy body disease (LBD) have ever been established. We showed that the plasma amyloid-β (Aβ) 1-42/Aβ1-40 ratio was significantly decreased in patients with Aβ+ LBD compared with those with Aβ- LBD and it might be a useful biomarker.
ISSN:1353-8020
1873-5126
DOI:10.1016/j.parkreldis.2023.105445