Low dose CTPA using a low kV technique combined with high IR: A clinical study

To investigate optimising a computerised tomography pulmonary angiogram (CTPA) scan protocol in terms of radiation dose and image quality using a low kV technique combined with high iterative reconstruction (IR) parameters (>50%) and apply the optimised protocol in clinical practice on patients irrespective of their body weight. CTPA examinations were performed on 64 patients equally divided into control and experimental groups. Patients in the control group were scanned using the current protocol (100 kV with 50% IR) while patients in the experimental group were scanned using an optimised protocol (80 kV with 60%IR). The radiation dose indices volume computerised tomography dose index (CTDIvol), dose length product (DLP), size specific dose estimates (SSDE) and effective dose (ED) were recorded. Subjective image quality was evaluated by 3 radiologists through absolute visual grading analysis (VGA) using an image quality scoring tool. The resultant image quality scores were analysed using Visual Grading Characteristics (VGC). Objective image quality was recorded in terms of contrast-to-noise-ratio (CNR) and signal-to-noise-ratio (SNR). The application of the optimised protocol resulted in a statistically significant (p