Vaccine Effectiveness of JYNNEOS against Mpox Disease in the United States

In this case–control study based on electronic health record data, 2193 patients with mpox were identified. JYNNEOS vaccine effectiveness was approximately 66% after two doses and 36% after one dose.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2023-06, Vol.388 (26), p.2434-2443
Hauptverfasser:	Deputy, Nicholas P., Deckert, Joseph, Chard, Anna N., Sandberg, Neil, Moulia, Danielle L., Barkley, Eric, Dalton, Alexandra F., Sweet, Cory, Cohn, Amanda C., Little, David R., Cohen, Adam L., Sandmann, Danessa, Payne, Daniel C., Gerhart, Jacqueline L., Feldstein, Leora R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Case-Control Studies Diagnosis Disease control Disease prevention Effectiveness Electronic health records Electronic medical records Gender identity Global Health HIV HIV Infections - epidemiology HIV Infections - prevention & control Homosexuality, Male Human immunodeficiency virus Humans Immunization Infections Infectious Disease Infectious Disease General Male Medical laboratories Minority & ethnic groups Mpox Mpox (monkeypox) - epidemiology Mpox (monkeypox) - prevention & control Non-binary gender Orthopoxvirus Prophylaxis Ratios Regression analysis Sexual and Gender Minorities - statistics & numerical data Sexually transmitted diseases Smallpox STD Transgender persons United States - epidemiology Vaccine efficacy Vaccine Efficacy - statistics & numerical data Vaccines Viral Infections
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Beschreibung
Zusammenfassung:	In this case–control study based on electronic health record data, 2193 patients with mpox were identified. JYNNEOS vaccine effectiveness was approximately 66% after two doses and 36% after one dose.
ISSN:	0028-4793 1533-4406 1533-4406
DOI:	10.1056/NEJMoa2215201