The role of NINJ1 protein in programmed cellular destruction

The protein NINJ1 drives membrane rupture associated with certain types of cell death. Investigation of NINJ1 reveals mechanistic details of how it functions, raising the possibility of developing new therapeutics. Insights into a mechanism that ruptures the plasma membrane.

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Bibliographische Detailangaben
Veröffentlicht in:	Nature (London) 2023-06, Vol.618 (7967), p.912-914
Hauptverfasser:	Whisstock, James C., Law, Ruby H. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/45 631/535 631/80 Cell Adhesion Molecules, Neuronal - metabolism Humanities and Social Sciences multidisciplinary Nerve Growth Factors - metabolism News And Views Science
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	The protein NINJ1 drives membrane rupture associated with certain types of cell death. Investigation of NINJ1 reveals mechanistic details of how it functions, raising the possibility of developing new therapeutics. Insights into a mechanism that ruptures the plasma membrane.
ISSN:	0028-0836 1476-4687
DOI:	10.1038/d41586-023-01602-z