Negative Homotropic Cooperativity in Guest Binding of a Trisporphyrin Double Cleft

Invited for the cover of this issue is the group of Takeharu Haino at Hiroshima University. The image depicts the host–guest complex of a trisporphyrin double cleft with an electron‐deficient aromatic molecule, which shows negative cooperativity in guest binding. Read the full text of the article at 10.1002/chem.202300107. “The cooperativity of artificial host–guest complexes has much potential for application to novel functional materials.” This and more about the story behind the front cover can be found in the article at 10.1002/chem.202300107).