Low grade cutaneous immune related adverse events leading to immunotherapy discontinuation

Cutaneous immune-related adverse events (cirAEs) are a common toxicity arising from the use of immune checkpoint inhibitors (ICIs) to treat cancer. We provide a case series of 10 patients who presented with low-severity cirAEs and who had their ICI discontinued against published guidelines, and we h...

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Veröffentlicht in:Clinical and experimental dermatology 2023-08, Vol.48 (9), p.1058-1060
Hauptverfasser: Jacoby, Ted V, Asdourian, Maria S, Shah, Nishi, Otto, Tracey S, Thompson, Leah L, Reynolds, Kerry L, Chen, Steven T
Format: Artikel
Sprache:eng
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Zusammenfassung:Cutaneous immune-related adverse events (cirAEs) are a common toxicity arising from the use of immune checkpoint inhibitors (ICIs) to treat cancer. We provide a case series of 10 patients who presented with low-severity cirAEs and who had their ICI discontinued against published guidelines, and we highlight areas for intervention to decrease the risk of this occurrence.
ISSN:0307-6938
1365-2230
DOI:10.1093/ced/llad180