Chinese validation of the quality of life profile for spinal deformities (QLPSD)

•We translated the Quality of Life Profile for Spine Deformities (QLPSD), an age-specific tool assessing the health-related quality of life (HRQoL) of adolescent patients with adolescent idiopathic scoliosis (AIS), from Spanish to Chinese.•The Chinese QLPSD shows adequate transcultural adaptation, reliability, and validity, and correlates well with the SRS-22.•The Chinese QLPSD proves useful as a clinical evaluation tool for the HRQoL of adolescent Chinese-speaking patients with AIS. We aimed to translate and validate the Quality of Life Profile for Spine Deformities (QLPSD), an age-specific tool assessing the individuals’ health-related quality of life (HRQoL), into a Chinese version for adolescent individuals with adolescent idiopathic scoliosis (AIS). The Chinese version was translated from the original Spanish QLPSD following widely accepted guidelines and evaluated by both individuals with AIS and experts. 172 Chinese-speaking individuals between 9 and 18 years of age with Cobb angles between 20° and 40° were included. Internal consistency, test–retest reliability, and floor and ceiling effects were all analyzed. Convergent validity was evaluated by correlating the measures in the Chinese QLPSD with those in the 22-item Scoliosis Research Society Questionnaire (SRS-22). Known-groups construct validity was assessed by comparing the QLPSD scores of two groups of individuals divided by their Cobb angles. The internal consistency (total Cronbach’s alpha = 0.917) and the test–retest reliability (total intra-class correlation coefficient = 0.896) were both satisfactory. The Chinese QLPSD correlated well with the SRS-22 in the total score and in relevant subscales (r = -0.572, p