Ocular retinal findings in asymptomatic patients with antiphospholipid syndrome secondary to systemic lupus erythematosus

Ocular retinal findings in asymptomatic patients with antiphospholipid syndrome secondary to systemic lupus erythematosus

The objective is to perform a multimodal ophthalmological evaluation, including optical coherence angiography (OCTA), asymptomatic APS secondary to SLE (APS/SLE), and compare to SLE patients and control group (CG). We performed a complete structural/functional ophthalmological evaluation using OCTA/...

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Veröffentlicht in:Clinical rheumatology 2023-08, Vol.42 (8), p.2105-2114
Hauptverfasser: Neto, Epitácio D. S., Neto, Taurino S. R., Signorelli, Flávio, Balbi, Gustavo G. M., Higashi, Alex H., Monteiro, Mário Luiz R., Bonfá, Eloisa, Andrade, Danieli C. O., Zacharias, Leandro C.
Format: Artikel
Sprache:eng
Schlagworte:
Angiography
Antiphospholipid antibodies
Antiphospholipid syndrome
Asymptomatic
Autoimmune diseases
Lupus
Medicine
Medicine & Public Health
Original Article
Retina
Rheumatology
Risk factors
Structure-function relationships
Systemic lupus erythematosus
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Zusammenfassung:The objective is to perform a multimodal ophthalmological evaluation, including optical coherence angiography (OCTA), asymptomatic APS secondary to SLE (APS/SLE), and compare to SLE patients and control group (CG). We performed a complete structural/functional ophthalmological evaluation using OCTA/microperimetry exam in all participants. One hundred fifty eyes/75 asymptomatic subjects [APS/SLE ( n  = 25), SLE ( n  = 25), and CG ( n  = 25)] were included. Ophthalmologic abnormalities occurred in 9 (36%) APS/SLE, 11 (44%) SLE, and none of CG ( p  
ISSN:0770-3198
1434-9949
DOI:10.1007/s10067-023-06613-9