Association of development quotient with nutritional status of vitamins B6, B12, and folate in 6–59-month-old children: Results from the Brazilian National Survey on Child Nutrition (ENANI-2019)

Vitamins B6, B12, and folate are essential for the formation and maintenance of the human brain, but studies evaluating these vitamins with early childhood development (ECD) in children under 5 y are limited and controversial. To evaluate the association between vitamins B6, B12, and folate concentr...

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Veröffentlicht in:The American journal of clinical nutrition 2023-07, Vol.118 (1), p.162-173
Hauptverfasser: Freitas-Costa, Nathalia Cristina, Andrade, Pedro Gomes, Normando, Paula, Nunes, Keronlainy Silva Salvatte, Raymundo, Carlos Eduardo, Castro, Inês Rugani Ribeiro de, Lacerda, Elisa Maria de Aquino, Farias, Dayana Rodrigues, Kac, Gilberto
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Sprache:eng
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Zusammenfassung:Vitamins B6, B12, and folate are essential for the formation and maintenance of the human brain, but studies evaluating these vitamins with early childhood development (ECD) in children under 5 y are limited and controversial. To evaluate the association between vitamins B6, B12, and folate concentrations/status and ECD. Data regarding 6520 children aged 6–59 mo from the ENANI-2019 (the Brazilian National Survey on Child Nutrition) were analyzed. ECD was assessed using the Survey of Well-being of Young Children’s milestones questionnaire. Vitamin B6 concentration (nmol/L) was classified according to the tertile of the distribution and with the cutoff 45.3 nmol/L were classified as high, and vitamin B12
ISSN:0002-9165
1938-3207
DOI:10.1016/j.ajcnut.2023.04.026