Chimeric receptors broaden the therapeutic landscape for autoimmune disease

Chimeric receptors broaden the therapeutic landscape for autoimmune disease

Emerging research suggests that chimeric antigen receptor T cell therapy could be an effective treatment for a range of difficult-to-treat autoimmune diseases, and sophisticated approaches are in tests, yet initial reports also highlight several questions that remain to be answered.

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Veröffentlicht in:Nature reviews. Rheumatology 2023-06, Vol.19 (6), p.327-328
Hauptverfasser: Finkel, Terri H., Radic, Marko
Format: Artikel
Sprache:eng
Schlagworte:
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Antigens
Arthritis
Autoimmune Diseases
Cell therapy
Chimeric antigen receptors
Cytotoxicity
Disease
Humans
Immunotherapy
Kinases
Lupus
Lymphocytes
Lymphocytes T
Medicine
Medicine & Public Health
News & Views
news-and-views
Patients
Plasma
Rheumatology
T cell receptors
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Beschreibung
Zusammenfassung:Emerging research suggests that chimeric antigen receptor T cell therapy could be an effective treatment for a range of difficult-to-treat autoimmune diseases, and sophisticated approaches are in tests, yet initial reports also highlight several questions that remain to be answered.
ISSN:1759-4790
1759-4804
DOI:10.1038/s41584-023-00968-8