Placental lesions associated with stillbirth by gestational age, according to feature importance: Results from the stillbirth collaborative research network

Previous studies have identified lesions commonly found in placentas associated with stillbirth but have not distinguished across a range of gestational ages (GAs). The objective of this study was to identify lesions associated with stillbirths at different GAs by adapting methods from the chemical...

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Veröffentlicht in:Placenta (Eastbourne) 2023-06, Vol.137, p.59-64
Hauptverfasser: Cersonsky, Tess E.K., Cersonsky, Rose K., Saade, George R., Silver, Robert M., Reddy, Uma M., Goldenberg, Robert L., Dudley, Donald J., Pinar, Halit
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Sprache:eng
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Zusammenfassung:Previous studies have identified lesions commonly found in placentas associated with stillbirth but have not distinguished across a range of gestational ages (GAs). The objective of this study was to identify lesions associated with stillbirths at different GAs by adapting methods from the chemical machine learning field to assign lesion importance based on correlation with GA. Placentas from the Stillbirth Collaborative Research Network were examined according to standard protocols. GAs at stillbirth were categorized as:
ISSN:0143-4004
1532-3102
DOI:10.1016/j.placenta.2023.04.005