Prior MRI-imaging impact of patients submitted to brachytherapy for prostate cancer

Brachytherapy for the treatment of prostate cancer is a well-established option. Use of Multiparametric Magnetic Resonance Imaging (mpMRI) for staging and diagnosis of prostate cancer has come to change the current paradigm. In this study we aim to assess the impact of performing mpMRI to evaluate t...

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Veröffentlicht in:Actas urológicas españolas (English ed.) 2023-10, Vol.47 (8), p.503-508
Hauptverfasser: Vieira e Brito, D., Fereira, A., Pereira, J., Pereira-Lourenço, M., Godinho, R., Pereira, B., Peralta, P., Conceiçao, P., Reis Mario, A., Paula Rabaça, C.
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Sprache:eng
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Zusammenfassung:Brachytherapy for the treatment of prostate cancer is a well-established option. Use of Multiparametric Magnetic Resonance Imaging (mpMRI) for staging and diagnosis of prostate cancer has come to change the current paradigm. In this study we aim to assess the impact of performing mpMRI to evaluate the presence of extracapsular lesions before brachytherapy in patients with prostate cancer concerning biochemical recurrence and time to nadir. Review data from 73 patients submitted to brachytherapy. The following factors were evaluated: age, initial PSA, MRI local staging results, ISUP, nadir, time to nadir, PSA at one-year, biochemical recurrence, and time to recurrence. Median age was 68 years (51–72) and median follow-up 53 months (30–72). Concerning imaging modality 30,1% (n = 22) patients performed mpMRI. In the mpMRI group, 90.9% (n = 20) had at least one suspect lesion on mpMRI. Time to nadir was 27 months (3–64) in patients where mpMRI was not performed and 23.5 months (2–48) in patients submitted to mpMRI (P = .244). The median value of nadir was 0.42 ng/mL (
ISSN:2173-5786
2173-5786
DOI:10.1016/j.acuroe.2023.04.009