Extracellular vesicles in vascular pathophysiology: beyond their molecular content

Extracellular vesicles (EVs) are released by all cells, both in physiological and pathological conditions. Their molecular charge and composition emerge as possible biomarkers, but EVs may also be considered for other clinical applications. This review discusses the role of other features of EVs, su...

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Veröffentlicht in:Polskie archiwum medycyny wewne̦trznej 2023-04, Vol.133 (4)
Hauptverfasser: Stępień, Ewa Ł, Durak-Kozica, Martyna, Moskal, Paweł
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Sprache:eng
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Zusammenfassung:Extracellular vesicles (EVs) are released by all cells, both in physiological and pathological conditions. Their molecular charge and composition emerge as possible biomarkers, but EVs may also be considered for other clinical applications. This review discusses the role of other features of EVs, such as their lipid components or composition of glycans that form the EV corona and regulate EV biodistribution and uptake by target cells. The importance of EV electric charge has been discussed as a new insight into EV fate and destination.
ISSN:1897-9483
1897-9483
DOI:10.20452/pamw.16483