Malignant epistaxis: a case wandering prostate cancer metastasis

In the appropriate clinical setting, the addition of IHC staining for NKX3.1, along with other prostate-restricted markers, may prove to be a valuable adjunct to definitively determine prostatic origin in poorly differentiated metastatic carcinomas. 5 Discussion Barbosa et al 2 indicated that very few paranasal metastases have been reported. Diagnosis is made by local biopsy and histopathological evaluation with immunohistochemical stains.3 Radiotherapy helps alleviate symptoms, such as bleeding and pain, which can diminish quality of life.4 Clinicians must be vigilant that the epistaxis can also be from a metastatic lesion. CS: provided contributions to the acquisition, analysis of data, drafting the work and had final approval of the version published.