Variation in Treatment of Pediatric Tuberculosis Infection in Different Provider Settings
To evaluate implementation of rifamycin-based regimens (RBR) for pediatric tuberculosis infection (TBI) treatment among 3 provider settings in a high-incidence county. A multicenter, retrospective observational study was performed across 3 sites in Los Angeles County: an academic center (AC), a gene...
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Veröffentlicht in: | The Journal of pediatrics 2023-08, Vol.259, p.113419-113419, Article 113419 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | To evaluate implementation of rifamycin-based regimens (RBR) for pediatric tuberculosis infection (TBI) treatment among 3 provider settings in a high-incidence county.
A multicenter, retrospective observational study was performed across 3 sites in Los Angeles County: an academic center (AC), a general pediatrics federally qualified health center (FQHC), and department of public health (DPH) tuberculosis clinics. Patients initiated on TBI treatment age 1 months to 17 years between 2018 and 2020 were included. RBRs were defined as regimens: 3 months of weekly rifapentine and isoniazid, 4 months of daily rifampin, and 3 months of daily isoniazid and rifampin.
We included 424 patients: 51 from AC, 327 from DPH, and 46 from FQHC. RBR use nearly doubled during the study period (from 43% in 2018 to 82% in 2020; P |
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ISSN: | 0022-3476 1097-6833 |
DOI: | 10.1016/j.jpeds.2023.113419 |