Improvement implant osseointegration through nonthermal Ar/O2 plasma

Improvement implant osseointegration through nonthermal Ar/O2 plasma

This study investigated the effects of nonthermal Ar/O2 plasma on the osseointegration of titanium implants. Through 8 weeks’ in vivo evaluation of implants inserted into femoral bones of male Sprague-Dawley rats, the new bone mineralization apposition rate (MAR) is increased by 1.87 and 2.14 times...

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Veröffentlicht in:Dental Materials Journal 2023/07/25, Vol.42(4), pp.461-468
Hauptverfasser: WU, Chengzan, YANG, Min, MA, Kai, ZHANG, Qian, BAI, Na, LIU, Yanshan
Format: Artikel
Sprache:eng
Schlagworte:
Apposition
Bone implants
Bone-implant interfaces
Hydrophilicity
Implants
Mineralization
New bone formation
Nonthermal plasma
Orthopaedic implants
Osseointegration
Oxygen plasma
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Zusammenfassung:This study investigated the effects of nonthermal Ar/O2 plasma on the osseointegration of titanium implants. Through 8 weeks’ in vivo evaluation of implants inserted into femoral bones of male Sprague-Dawley rats, the new bone mineralization apposition rate (MAR) is increased by 1.87 and 2.14 times for implants of smooth machined (SM) and sand-blasted and acid-etched (SLA) after plasma treatment. The bone volume fraction (bone volume/total volume, BV/TV) and bone-implant contact (BIC) ratios are improved by 1.31, 1.26 times and 1.35, 1.15 times after 90 s plasma treatment. The improved hydrophilicity rather than implant surface morphology is believed to play a critical role for the osseointegration improvement.
ISSN:0287-4547
1881-1361
DOI:10.4012/dmj.2022-158