Epidemiological and clinical features of the 2016–2018 Zika virus outbreak in northern Argentina

Epidemiological and clinical features of the 2016–2018 Zika virus outbreak in northern Argentina

ABSTRACT Background During the American epidemic, Zika virus (ZIKV) expanded rapidly through dengue virus (DENV)-endemic regions. We analyzed the presentation of ZIKV infection in patients from the City of Orán, Argentina, and compared some of its features with dengue presentation in the same region...

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Veröffentlicht in:Transactions of the Royal Society of Tropical Medicine and Hygiene 2023-08, Vol.117 (8), p.561-568
Hauptverfasser: Byrne, Alana B, Bonnin, Florencia A, Bruno, Agostina, Bono, María Manuela, Contrini, María Marta, López, Eduardo L, Quipildor, Marcelo O, Talarico, Laura B
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies, Viral
Argentina - epidemiology
Cross Reactions
Dengue - diagnosis
Dengue Virus
Disease Outbreaks
Female
Humans
Retrospective Studies
Zika Virus
Zika Virus Infection - diagnosis
Zika Virus Infection - epidemiology
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Zusammenfassung:ABSTRACT Background During the American epidemic, Zika virus (ZIKV) expanded rapidly through dengue virus (DENV)-endemic regions. We analyzed the presentation of ZIKV infection in patients from the City of Orán, Argentina, and compared some of its features with dengue presentation in the same region. Methods A retrospective study was conducted at San Vicente de Paul Hospital during 2016–2018. Clinical and demographic characteristics, pre-existing immunity to DENV, viral load and type I interferon (IFN) responses were studied in 63 patients with ZIKV infection. Results Clinical manifestations of ZIKV infection were generally mild compared with dengue, although rash (p
ISSN:0035-9203
1878-3503
DOI:10.1093/trstmh/trad013