Functional Role of an Unusual Transmembrane Acidic Residue in the Calcium Pump Regulator Myoregulin

Myoregulin (MLN) is a member of the regulin family, a group of homologous membrane proteins that bind to and regulate the activity of the sarcoplasmic reticulum Ca2+-ATPase (SERCA). MLN, which is expressed in skeletal muscle, contains an acidic residue in its transmembrane domain. The location of th...

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Veröffentlicht in:	Biochemistry (Easton) 2023-04, Vol.62 (8), p.1331-1336
Hauptverfasser:	Liu, Andy Y., Rathod, Nishadh, Guerrero-Serna, Guadalupe, Young, Howard S., Espinoza-Fonseca, L. Michel
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcium - metabolism Calcium-Binding Proteins - chemistry Humans Ion Transport Molecular Conformation Muscle, Skeletal - metabolism Sarcoplasmic Reticulum - chemistry Sarcoplasmic Reticulum - metabolism Sarcoplasmic Reticulum Calcium-Transporting ATPases - chemistry Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism
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