Surgical management of dermatofibrosarcoma protuberans

Surgical management of dermatofibrosarcoma protuberans

Dermatofibrosarcoma protuberans (DFSP) is an uncommon, locally aggressive cutaneous malignancy. Complete resection is the primary treatment but there is debate over the optimal method. Wide local excision was traditionally the standard of care; however, National Comprehensive Cancer Network guidelin...

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Veröffentlicht in:Journal of surgical oncology 2023-07, Vol.128 (1), p.87-96
Hauptverfasser: Rust, Dylan J., Kwinta, Bradley D., Geskin, Larisa J., Samie, Faramarz H., Remotti, Fabrizio, Yoon, Sam S.
Format: Artikel
Sprache:eng
Schlagworte:
dermatofibrosarcoma protuberans
Mohs micrographic surgery
Sarcoma
surgery
wide local excision
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Zusammenfassung:Dermatofibrosarcoma protuberans (DFSP) is an uncommon, locally aggressive cutaneous malignancy. Complete resection is the primary treatment but there is debate over the optimal method. Wide local excision was traditionally the standard of care; however, National Comprehensive Cancer Network guidelines now recommend Mohs micrographic surgery as the preferred approach. Medical therapy with imatinib can be used in advanced or unresectable disease. This review will discuss the current management of DFSP, focusing on optimal surgical approach.
ISSN:0022-4790
1096-9098
DOI:10.1002/jso.27258