Sugarcane wastes as microbial feedstocks: A review of the biorefinery framework from resource recovery to production of value-added products

[Display omitted] •Sugarcane wastes, cost-effective crop residues, are promising microbial feedstocks.•Pretreatment processes are critical for the successful biorefinery of sugarcane wastes.•Sugarcane bagasse, molasses, and straw are representative sugarcane-based wastes as carbon sources for bioconversion.•Strategies for converting sugarcane wastes into value-added products were discussed. Sugarcane industry is a major agricultural sector capable of producing sugars with byproducts including straw, bagasse, and molasses. Sugarcane byproducts are no longer wastes since they can be converted into carbon-rich resources for biorefinery if pretreatment of these is well established. Considerable efforts have been devoted to effective pretreatment techniques for each sugarcane byproduct to supply feedstocks in microbial fermentation to produce value-added fuels, chemicals, and polymers. These value-added chains, which start with low-value industrial wastes and end with high-value products, can make sugarcane-based biorefinery a more viable option for the modern chemical industry. In this review, recent advances in sugarcane valorization techniques are presented, ranging from sugarcane processing, pretreatment, and microbial production of value-added products. Three lucrative products, ethanol, 2,3-butanediol, and polyhydroxyalkanoates, whose production from sugarcane wastes has been widely researched, are being explored. Future studies and development in sugarcane waste biorefinery are discussed to overcome the challenges remaining.