Synthesis of fused bis-indazoles/indazoles via a one-pot sequential strategy
We report here an efficient synthesis of fused bis-indazoles/indazoles a one-pot sequential strategy starting from -azido aldehydes and amines. This novel method involves the sequential formation of 2 -indazole followed by a Pd-catalyzed intramolecular cross-dehydrogenative coupling reaction. Overal...
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Veröffentlicht in: | Organic & biomolecular chemistry 2023-03, Vol.21 (13), p.2816-2821 |
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Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | We report here an efficient synthesis of fused bis-indazoles/indazoles
a one-pot sequential strategy starting from
-azido aldehydes and amines. This novel method involves the sequential formation of 2
-indazole followed by a Pd-catalyzed intramolecular cross-dehydrogenative coupling reaction. Overall, this one-pot sequential reaction involved the formation of new five bonds, resulting in the formation of three heterocyclic rings. |
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ISSN: | 1477-0520 1477-0539 |
DOI: | 10.1039/d3ob00121k |