Micro- and nanoplastic toxicity: A review on size, type, source, and test-organism implications

Polymeric wastes are among the current major environmental problems due to potential pollution and contamination. Within the spectrum of polymeric waste, microplastics (MPs) and nanoplastics (NPs) have gained ground in recent research since these particles can affect the local biota, inducing toxic effects on several organisms. Different outcomes have been reported depending on particle sizes, shape, types, and exposed organisms and conditions, among other variables. This review aimed to compile and discuss the current knowledge and possible literature gaps regarding the MPs and NPs generation and their toxicological effects as stressors, considering polymer type (as polyethylene, polypropylene, polyethylene terephthalate, polystyrene, polyvinyl chloride, or others), size (micro- or nano-scale), source (commercial, lab-synthesized, or environmental) and test organism group. In that sense, 615 publications were analyzed, among which 72 % discussed micro-sized plastics, while