Rates and predictors of 30‐day hospital readmissions in adults for drug‐induced acute pancreatitis: A retrospective study from the United States National Readmission Database

Background and Aim Drug‐induced acute pancreatitis (DIAP) linked to several medications is a diagnosis of exclusion and is associated with significant morbidity and mortality, contributing to the US healthcare cost burden. Existing studies on DIAP focus on the drug classes that can cause acute pancr...

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Veröffentlicht in:Journal of gastroenterology and hepatology 2023-08, Vol.38 (8), p.1277-1282
Hauptverfasser: Ebhohon, Ebehiwele, Khoshbin, Katayoun, Shaka, Hafeez
Format: Artikel
Sprache:eng
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Zusammenfassung:Background and Aim Drug‐induced acute pancreatitis (DIAP) linked to several medications is a diagnosis of exclusion and is associated with significant morbidity and mortality, contributing to the US healthcare cost burden. Existing studies on DIAP focus on the drug classes that can cause acute pancreatitis. Hence, our retrospective study aims to determine the rates and predictors for 30‐day readmissions (30‐DR) in patients with index hospitalization for DIAP. Methods From the Nationwide Readmissions Database, we followed adults admitted for DIAP who were discharged alive for 30 days. During 30‐DR, we evaluated the rates, predictors, and outcomes of DIAP. Results Of the 4457 DIAP patients surviving at discharge, 12.5% were readmitted at 30 days. During readmissions, the predictors of 30‐DR for DIAP were young age, the Charlson–Deyo Comorbidity Index of 2 and 3, protein‐energy malnutrition, and dyslipidemia. During 30‐DR, DIAP had a higher mortality rate (2.4% vs. 0.7%; P 
ISSN:0815-9319
1440-1746
DOI:10.1111/jgh.16177