Photocatalytic and Enhanced Biological Activities of Schiff Base Capped Fluorescent CdS Nanoparticles

In the present work, biocompatible CdS nanoparticles were synthesized using Schiff base ligand, 3-((2-(-(1-(2hydroxyphenyl)ethylidene)amino)ethyl)imino)-2-pentone, by a simple ultrasonic irradiation method. The structural, morphological, and optical properties were studied using XRD, SEM, TEM, UV–visible absorption, and photoluminescence (PL) spectra. The quantum confinement effect of the Schiff base capped CdS nanoparticles was confirmed by using UV–visible and PL spectrum analysis. This CdS nanoparticles were an effective photocatalyst for degrading rhodamine 6G and methylene blue with a 70% and 98% degradation capacity, respectively. Furthermore, the disc-diffusion method demonstrated that CdS nanoparticles inhibit G-positive bacteria and G-negative bacteria more effectively. These Schiff base capped CdS nanoparticles were taken for an in-vitro experiment with HeLa cells to exhibit the possibility of providing optical probes in biological applications and observed under a fluorescence microscope. In addition, MTT cell viability assays were carried out to investigate the cytotoxicity for 24 h. As a result of this study, 2.5 µg/ml doses of CdS nanoparticles are suitable for imaging and are effective in destroying HeLa cells. The present study suggests that the synthesized Schiff base capped CdS nanoparticles could be a potential photocatalyst, antibacterial agent, and biocompatible nanoparticle for bioimaging applications.