One-Pot Synthesis of Core Structure of Shewanelline C Using an Azidoindoline
The unprecedented synthesis of the indolines bearing N3-quinazolin-2,4-dione moiety using an AZIN is reported. The concise synthesis features the tandem Staudinger/chemo-selective aza-Wittig/cyclization sequence of AZINs with isatoic anhydride by a one-pot protocol.
Gespeichert in:
| Veröffentlicht in: | Journal of organic chemistry 2023-03, Vol.88 (6), p.3992-3997 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | The unprecedented synthesis of the indolines bearing N3-quinazolin-2,4-dione moiety using an AZIN is reported. The concise synthesis features the tandem Staudinger/chemo-selective aza-Wittig/cyclization sequence of AZINs with isatoic anhydride by a one-pot protocol. |
|---|---|
| ISSN: | 0022-3263 1520-6904 |
| DOI: | 10.1021/acs.joc.3c00013 |