A ratiometric fluorescent probe for fast detection and bioimaging of formaldehyde
A novel ratiometric probe ( SWJT-10 ) based on isophorone derivatives has been designed and synthesized for the detection of formaldehyde (FA). This probe displayed an obvious ratiometric fluorescence response to FA with a blue shift from the NIR (680 nm) to the yellow light region (600 nm) in aqueo...
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| Veröffentlicht in: | Organic & biomolecular chemistry 2023-03, Vol.21 (1), p.2167-2171 |
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| container_title | Organic & biomolecular chemistry |
| container_volume | 21 |
| creator | Lin, Nai-Jie Wu, Huan Peng, Jing Yang, Shu-Han Tan, Rui Peng, Yu Wang, Ya-Wen |
| description | A novel ratiometric probe (
SWJT-10
) based on isophorone derivatives has been designed and synthesized for the detection of formaldehyde (FA). This probe displayed an obvious ratiometric fluorescence response to FA with a blue shift from the NIR (680 nm) to the yellow light region (600 nm) in aqueous solution. And it showed good selectivity, high sensitivity and a fast response to FA (less than 5 s) due to a new recognition mechanism. Moreover,
SWJT-10
has been applied to monitor FA in living cells and zebrafish.
A novel ratiometric fluorescent probe has been developed for rapid detection of formaldehyde based on a new recognition mechanism. |
| doi_str_mv | 10.1039/d2ob02314h |
| format | Article |
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SWJT-10
) based on isophorone derivatives has been designed and synthesized for the detection of formaldehyde (FA). This probe displayed an obvious ratiometric fluorescence response to FA with a blue shift from the NIR (680 nm) to the yellow light region (600 nm) in aqueous solution. And it showed good selectivity, high sensitivity and a fast response to FA (less than 5 s) due to a new recognition mechanism. Moreover,
SWJT-10
has been applied to monitor FA in living cells and zebrafish.
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SWJT-10
) based on isophorone derivatives has been designed and synthesized for the detection of formaldehyde (FA). This probe displayed an obvious ratiometric fluorescence response to FA with a blue shift from the NIR (680 nm) to the yellow light region (600 nm) in aqueous solution. And it showed good selectivity, high sensitivity and a fast response to FA (less than 5 s) due to a new recognition mechanism. Moreover,
SWJT-10
has been applied to monitor FA in living cells and zebrafish.
A novel ratiometric fluorescent probe has been developed for rapid detection of formaldehyde based on a new recognition mechanism.</description><subject>Animals</subject><subject>Aqueous solutions</subject><subject>Fluorescence</subject><subject>Fluorescent Dyes</subject><subject>Fluorescent indicators</subject><subject>Formaldehyde</subject><subject>HeLa Cells</subject><subject>Humans</subject><subject>Medical imaging</subject><subject>Selectivity</subject><subject>Zebrafish</subject><issn>1477-0520</issn><issn>1477-0539</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpd0c1LwzAYBvAgitPpxbsS8CLCNG2ypDnO-TFhMAQ9lzR5s3W0zUzaw_57sw8neEogP16ePC9CVwl5SAiVjyZ1BUlpwhZH6CxhQgzIkMrjwz0lPXQewpKQRArOTlGPciGlIPIMfYywV23pamh9qbGtOuchaGhavPKuAGydx1aFFhtoQUfZYNUYXJSurNW8bObY2Q2qVWVgsTZwgU6sqgJc7s8--np9-RxPBtPZ2_t4NB1oSkU7UDyxDGJOJcBIqzNSyKES2jBLlCXcWk0oNwrSjDLGAbjimaXDQhkmQALto7vd3Jjzu4PQ5nUZg1eVasB1IU9FxjIqJSeR3v6jS9f5JqbbqpQIKkRU9zulvQvBg81XPv7Rr_OE5Jui8-d09rQtehLxzX5kV9RgDvS32Qiud8AHfXj92xT9AbeagxU</recordid><startdate>20230308</startdate><enddate>20230308</enddate><creator>Lin, Nai-Jie</creator><creator>Wu, Huan</creator><creator>Peng, Jing</creator><creator>Yang, Shu-Han</creator><creator>Tan, Rui</creator><creator>Peng, Yu</creator><creator>Wang, Ya-Wen</creator><general>Royal Society of Chemistry</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7T7</scope><scope>7TM</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-3862-632X</orcidid><orcidid>https://orcid.org/0000-0003-2582-8886</orcidid><orcidid>https://orcid.org/0000-0002-7795-1141</orcidid></search><sort><creationdate>20230308</creationdate><title>A ratiometric fluorescent probe for fast detection and bioimaging of formaldehyde</title><author>Lin, Nai-Jie ; Wu, Huan ; Peng, Jing ; Yang, Shu-Han ; Tan, Rui ; Peng, Yu ; Wang, Ya-Wen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c337t-a61f4e539a7ed9fc80b95a7cd4f0af06ffc036dae283446ee6a68f35bad47e9e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Animals</topic><topic>Aqueous solutions</topic><topic>Fluorescence</topic><topic>Fluorescent Dyes</topic><topic>Fluorescent indicators</topic><topic>Formaldehyde</topic><topic>HeLa Cells</topic><topic>Humans</topic><topic>Medical imaging</topic><topic>Selectivity</topic><topic>Zebrafish</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lin, Nai-Jie</creatorcontrib><creatorcontrib>Wu, Huan</creatorcontrib><creatorcontrib>Peng, Jing</creatorcontrib><creatorcontrib>Yang, Shu-Han</creatorcontrib><creatorcontrib>Tan, Rui</creatorcontrib><creatorcontrib>Peng, Yu</creatorcontrib><creatorcontrib>Wang, Ya-Wen</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Organic & biomolecular chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lin, Nai-Jie</au><au>Wu, Huan</au><au>Peng, Jing</au><au>Yang, Shu-Han</au><au>Tan, Rui</au><au>Peng, Yu</au><au>Wang, Ya-Wen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A ratiometric fluorescent probe for fast detection and bioimaging of formaldehyde</atitle><jtitle>Organic & biomolecular chemistry</jtitle><addtitle>Org Biomol Chem</addtitle><date>2023-03-08</date><risdate>2023</risdate><volume>21</volume><issue>1</issue><spage>2167</spage><epage>2171</epage><pages>2167-2171</pages><issn>1477-0520</issn><eissn>1477-0539</eissn><abstract>A novel ratiometric probe (
SWJT-10
) based on isophorone derivatives has been designed and synthesized for the detection of formaldehyde (FA). This probe displayed an obvious ratiometric fluorescence response to FA with a blue shift from the NIR (680 nm) to the yellow light region (600 nm) in aqueous solution. And it showed good selectivity, high sensitivity and a fast response to FA (less than 5 s) due to a new recognition mechanism. Moreover,
SWJT-10
has been applied to monitor FA in living cells and zebrafish.
A novel ratiometric fluorescent probe has been developed for rapid detection of formaldehyde based on a new recognition mechanism.</abstract><cop>England</cop><pub>Royal Society of Chemistry</pub><pmid>36799709</pmid><doi>10.1039/d2ob02314h</doi><tpages>5</tpages><orcidid>https://orcid.org/0000-0002-3862-632X</orcidid><orcidid>https://orcid.org/0000-0003-2582-8886</orcidid><orcidid>https://orcid.org/0000-0002-7795-1141</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1477-0520 |
| ispartof | Organic & biomolecular chemistry, 2023-03, Vol.21 (1), p.2167-2171 |
| issn | 1477-0520 1477-0539 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2784839960 |
| source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Animals Aqueous solutions Fluorescence Fluorescent Dyes Fluorescent indicators Formaldehyde HeLa Cells Humans Medical imaging Selectivity Zebrafish |
| title | A ratiometric fluorescent probe for fast detection and bioimaging of formaldehyde |
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