Bat crazy iPSCs

Accelerating the development of tools for non-model animal research, Dejosez et al. report the generation of induced pluripotent stem cells (iPSCs) from bats using a modified Yamanaka protocol. Their study also reveals that bat genomes harbor diverse and unusually abundant endogenous retroviruses (E...

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Veröffentlicht in:	Cell 2023-03, Vol.186 (5), p.901-903
Hauptverfasser:	Athar, Fathima, Seluanov, Andrei, Gorbunova, Vera
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chiroptera Endogenous Retroviruses Induced Pluripotent Stem Cells
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Accelerating the development of tools for non-model animal research, Dejosez et al. report the generation of induced pluripotent stem cells (iPSCs) from bats using a modified Yamanaka protocol. Their study also reveals that bat genomes harbor diverse and unusually abundant endogenous retroviruses (ERVs) that are reactivated during iPSC reprogramming. Accelerating the development of tools for non-model animal research, Dejosez et al. report the generation of induced pluripotent stem cells (iPSCs) from bats using a modified Yamanaka protocol. Their study also reveals that bat genomes harbor diverse and unusually abundant endogenous retroviruses (ERVs) that are reactivated during iPSC reprogramming.
ISSN:	0092-8674 1097-4172
DOI:	10.1016/j.cell.2023.01.033