Correlation between visuo-cognitive tests and simulator performance of commercial drivers in the United States

•This study aimed to identify the visuo-cognitive tests and self-reported driving history that correlate with the Cumulative Simulator Score among 31 active drivers with valid commercial driver’s licenses (CDL).•Ninety percent of participants were male, average age 53 years, CDL driving experience 21 years, 14 years of education, low medication usage, and strong performance on the visuo-cognitive tests.•The number of tickets as a CDL driver and the number of years of education had the most correlations with the Cumulative Simulator Score.•A higher number of pedestrians hit on the simulator correlated with more experience as a commercial driver, higher MOCA scores, and Trail Making Test-A time.•This data may help guide the future development of advanced screening tools to better evaluate commercial driver safety. Future steps include a more targeted study, narrowed to the significant variables, with a larger sample size. Driving commercial vehicles requires intact visuo-cognitive skills. Approximately 13% of all fatal motor vehicle crashes in the United States involve commercial drivers. The ability to accurately predict risk factors for unsafe commercial driving is essential for public safety. Accurate prediction tools will advance the field of commercial driver science, provide policy guidance for driver testing and assist healthcare providers during testing. Prior studies have correlated clinical tools to roadway safety; translating these results to commercial drivers has not yet been done. This study aimed to identify specific demographic, driving history and visuo-cognitive test results that correlate with driving simulator performance. Using the Cumulative Simulator Score (CSS) as a surrogate for driving ability, the objective was to correlate both sets of data (self-reported and visuo-cognitive testing) with the CSS to identify screening tools for unsafe driving in commercial drivers. Principal Results. Baseline assessments of 120 variables were collected from October 2020 to January 2022. Of the 31 participants, 3 were female and 28 were male with a mean age of 53 years. Average BMI was 32, blood pressure 136/84, 32 years of CDL driving experience, 36,500 annual CDL mileage, 11,000 annual personal mileage, 14 years of education, average number of medications: 2, average number of medical conditions: 2, six participants with personal and/or commercial crashes or tickets in past five years, MOCA 27/30, Trails B time 66 s, UFOV Speed of Processing 15 m