Pallidal Beta Activity Is Linked to Stimulation‐Induced Slowness in Dystonia
ABSTRACT Background Pallidal deep brain stimulation (DBS) effectively alleviates symptoms in dystonia patients, but may induce movement slowness as a side‐effect. In Parkinson's disease, hypokinetic symptoms have been associated with increased beta oscillations (13–30 Hz). We hypothesize that t...
Gespeichert in:
Veröffentlicht in: | Movement disorders 2023-05, Vol.38 (5), p.894-899 |
---|---|
Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | ABSTRACT
Background
Pallidal deep brain stimulation (DBS) effectively alleviates symptoms in dystonia patients, but may induce movement slowness as a side‐effect. In Parkinson's disease, hypokinetic symptoms have been associated with increased beta oscillations (13–30 Hz). We hypothesize that this pattern is symptom‐specific, thus accompanying DBS‐induced slowness in dystonia.
Methods
In 6 dystonia patients, pallidal rest recordings with a sensing‐enabled DBS device were performed and tapping speed was assessed using marker‐less pose estimation over 5 time points following cessation of DBS.
Results
After cessation of pallidal stimulation, movement speed increased over time (P |
---|---|
ISSN: | 0885-3185 1531-8257 |
DOI: | 10.1002/mds.29347 |