Trial of Endovascular Thrombectomy for Large Ischemic Strokes

In a trial involving patients with large acute strokes, endovascular thrombectomy resulted in better functional outcomes than medical care alone but was associated with vascular complications.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2023-04, Vol.388 (14), p.1259-1271
Hauptverfasser:	Sarraj, Amrou, Hassan, Ameer E., Abraham, Michael G., Ortega-Gutierrez, Santiago, Kasner, Scott E., Hussain, M. Shazam, Chen, Michael, Blackburn, Spiros, Sitton, Clark W., Churilov, Leonid, Sundararajan, Sophia, Hu, Yin C., Herial, Nabeel A., Jabbour, Pascal, Gibson, Daniel, Wallace, Adam N., Arenillas, Juan F., Tsai, Jenny P., Budzik, Ronald F., Hicks, William J., Kozak, Osman, Yan, Bernard, Cordato, Dennis J., Manning, Nathan W., Parsons, Mark W., Hanel, Ricardo A., Aghaebrahim, Amin N., Wu, Teddy Y., Cardona-Portela, Pere, Pérez de la Ossa, Natalia, Schaafsma, Joanna D., Blasco, Jordi, Sangha, Navdeep, Warach, Steven, Gandhi, Chirag D., Kleinig, Timothy J., Sahlein, Daniel, Elijovich, Lucas, Tekle, Wondwossen, Samaniego, Edgar A., Maali, Laith, Abdulrazzak, M. Ammar, Psychogios, Marios N., Shuaib, Ashfaq, Pujara, Deep K., Shaker, Faris, Johns, Hannah, Sharma, Gagan, Yogendrakumar, Vignan, Ng, Felix C., Rahbar, Mohammad H., Cai, Chunyan, Lavori, Philip, Hamilton, Scott, Nguyen, Thanh, Fifi, Johanna T., Davis, Stephen, Wechsler, Lawrence, Pereira, Vitor M., Lansberg, Maarten G., Hill, Michael D., Grotta, James C., Ribo, Marc, Campbell, Bruce C., Albers, Gregory W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Brain Ischemia - diagnostic imaging Brain Ischemia - drug therapy Brain Ischemia - surgery Cardiovascular system Carotid arteries Carotid artery Carotid Artery Diseases - complications Cerebral blood flow Cerebral Hemorrhage - chemically induced Cerebral Hemorrhage - etiology Cerebral infarction Clinical trials Computed tomography Edema Emergency Medicine Endovascular Procedures - adverse effects Endovascular Procedures - methods Fibrinolytic Agents - adverse effects Fibrinolytic Agents - therapeutic use Hemorrhage Humans Infarction, Middle Cerebral Artery - complications Ischemia Ischemic Stroke - diagnostic imaging Ischemic Stroke - drug therapy Ischemic Stroke - surgery Magnetic resonance imaging Neurology Neurosurgery Patient safety Prospective Studies Radiology Radiology General Recovery of Function Software Stroke Stroke - diagnostic imaging Stroke - drug therapy Stroke - surgery Thrombectomy - adverse effects Thrombectomy - methods Tomography Treatment Outcome Vasoconstriction Veins & arteries
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Beschreibung
Zusammenfassung:	In a trial involving patients with large acute strokes, endovascular thrombectomy resulted in better functional outcomes than medical care alone but was associated with vascular complications.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa2214403