Harnessing the omics revolution to address the global biodiversity crisis

Human disturbances are altering global biodiversity in unprecedented ways. We identify three fundamental challenges underpinning our understanding of global biodiversity (namely discovery, loss, and preservation), and discuss how the omics revolution (e.g. genomics, transcriptomics, proteomics, metabolomics, and meta-omics) can help address these challenges. We also discuss how omics tools can illuminate the major drivers of biodiversity loss, including invasive species, pollution, urbanization, overexploitation, and climate change, with a special focus on highly diverse tropical environments. Although omics tools are transforming the traditional toolkit of biodiversity research, their application to addressing the current biodiversity crisis remains limited and may not suffice to offset current rates of biodiversity loss. Despite technical and logistical challenges, omics tools need to be fully integrated into global biodiversity research, and better strategies are needed to improve their translation into biodiversity policy and practice. It is also important to recognize that although the omics revolution can be considered the biologist’s dream, socioeconomic disparity limits their application in biodiversity research. [Display omitted] •Human disturbances are driving the current biodiversity crisis.•Fundamental biodiversity challenges include biodiversity discovery, loss, and preservation.•The omics revolution is transforming the traditional toolkit of biodiversity research.•Gaps exist in the application of omics tools to addressing biodiversity crisis.•We need to improve translation of omics research into biodiversity policy and practice.