Patient reported pregnancy and birth outcomes in genetic neuromuscular diseases

•Miscarriage and interventional delivery more common in neuromuscular disease.•Non-ambulant report more miscarriage and intervention than ambulant patients.•Gestational hypertension common in LGMD2A and myotonic dystrophy.•Falls during pregnancy common and risk should be addressed.•Specialist peri‑natal input should be considered for all. Pregnancy and birth in women with neuromuscular conditions has been associated with more rapid disease progression and obstetric complications. This study assessed the impact of functional status and specific diagnosis on patient reported pregnancy and birth outcomes in 26 genetic neuromuscular diseases. Pregnancy and birth outcomes were collected through electronic patient questionnaires and analysed by mobility group and diagnosis. Free text responses were grouped into themes. 721 pregnancies were reported by 305 women. Miscarriage (21% of pregnancies), caesarean delivery (38% of births) and instrumental vaginal delivery (19% of births) were all more frequent in respondents than in the general population (p