A comparison of study on intestinal barrier protection of polysaccharides from Hericium erinaceus before and after fermentation

A comparison of study on intestinal barrier protection of polysaccharides from Hericium erinaceus before and after fermentation

The intestinal barrier protects the host from harmful substances. This paper investigated two polysaccharides extracted from the Hericium erinaceus before and after fermentation (HEP and FHEP). The effects of two polysaccharides on the intestinal barrier were investigated in cell and mice models. Th...

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Veröffentlicht in:International journal of biological macromolecules 2023-04, Vol.233, p.123558-123558, Article 123558
Hauptverfasser: Su, Yue, Cheng, Shasha, Ding, Yixin, Wang, Linge, Sun, Mingshuang, Man, Chaoxin, Zhang, Yu, Jiang, Yujun
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Fermentation
Fermented
Gut microbiota
Intestinal barrier
Intestinal Mucosa - metabolism
Intestines
Mice
Polysaccharide
Polysaccharides - metabolism
Polysaccharides - pharmacology
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Zusammenfassung:The intestinal barrier protects the host from harmful substances. This paper investigated two polysaccharides extracted from the Hericium erinaceus before and after fermentation (HEP and FHEP). The effects of two polysaccharides on the intestinal barrier were investigated in cell and mice models. The results showed that polysaccharides had a protective effect against acrylamide-induced injury in IEC-6 cell. Compared with HEP, FHEP significantly increased TEER and paracellular permeability (P 
ISSN:0141-8130
1879-0003
DOI:10.1016/j.ijbiomac.2023.123558