Effectiveness of a Meningococcal Group B Vaccine (4CMenB) in Children

In this case–control study of all meningococcal cases in Spain between 2015 and 2019, full vaccination with meningococcal serogroup B vaccine was 76% effective in preventing meningococcal diseases.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2023-02, Vol.388 (5), p.427-438
Hauptverfasser:	Castilla, Jesús, García Cenoz, Manuel, Abad, Raquel, Sánchez-Cambronero, Laura, Lorusso, Nicola, Izquierdo, Conchita, Cañellas Llabrés, Soledad, Roig, Javier, Malvar, Alberto, González Carril, Fernando, Boone, An L.D., Pérez Martín, Jaime, Rodríguez Recio, M. Jesús, Galmés, Antònia, Caballero, Arturo, García Rojas, Amós, Juanas, Felipe, Nieto, Mercedes, Viloria Raymundo, Luis J., Martínez Ochoa, Eva, Rivas, Ana I., Castrillejo, Daniel, Moreno Pérez, David, Martínez, Ana, Borràs, Eva, Sánchez Gómez, Amaya, Pastor, Eliseo, Nartallo, Victoria, Arteagoitia, José M., Álvarez-Fernández, Blanca, García Pina, Rocío, Fernández Arribas, Socorro, Vanrell, Joana, García Hernández, Sara, Mendoza, Rita M., Méndez, Manuel, López-Tercero, M. Mar, Fernández-Rodríguez, Ángela, Blanco, Ángela, Carrillo de Albornoz, F. Javier, Ruiz Olivares, José, Ruiz-Montero, Rafael, Limia, Aurora, Navarro-Alonso, José A., Vázquez, Julio A., Barricarte, Aurelio
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Antigens Bacterial Infections Case-Control Studies Child Childhood Diseases Children Global Health Humans Immunization Infant Infectious Disease Infectious Disease General Intensive care Invasive meningococcal disease Laboratories Meningococcal disease Meningococcal Infections - microbiology Meningococcal Infections - prevention & control Meningococcal Vaccines - therapeutic use Neisseria meningitidis Neisseria meningitidis, Serogroup B Patients Pediatrics Pediatrics General Spain Surveillance Vaccine efficacy Vaccines
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Beschreibung
Zusammenfassung:	In this case–control study of all meningococcal cases in Spain between 2015 and 2019, full vaccination with meningococcal serogroup B vaccine was 76% effective in preventing meningococcal diseases.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa2206433