A Review on Schiff Base as a Versatile Fluorescent Chemo-sensors Tool for Detection of Cu2+ and Fe3+ Metal Ion

Schiff bases as fluorescent Chemo-sensors fluorogenic cation sensors is scientifically exigent work. Recently Schiff bases derivatives gained more attention because of their structural variability. Donor and acceptor group joint with delocalized π -orbital display excellent fluorescent properties due to intramolecular charge transfer (ICT). Schiff bases coordinate with the metal ions resulting in a small change of photophysical properties and typical sensing behavior hypochromic/hyperchromic or hypsochromic/bathochromic shift. In this review, we endeavored to converge the beforehand reported Schiff baes-derived sensors and investigated the probes' design, synthesis, ON/OFF & OFF/ON Fe 3+ and Cu 2+ metal ion sensing mechanism, and practical application. This review focuses on the synthesis of Schiff baes as fluorescent Chemosensor for investigation of Fe and Cu metal ions during the period of over the two past decade (2003–2022). We anticipate that this review will provide a fundamental framework for researchers to further investigate the topic of Schiff-based sensors for metal ion detection.