Profiles of TBI Injury Severity as Predictors of Functional Outcomes and Well-being Outcomes

To identify profiles of traumatic brain injury (TBI) severity and relate profiles to functional and well-being outcomes. Longitudinal observational study with assessments during acute rehabilitation, discharge, and one year after injury. Santa Clara Valley Medical Center (SCVMC) acute inpatient rehabilitation and general community setting. Three hundred and seventy-nine individuals [76.8% male; mean(std) age= 34.6(16.9) years] in the Traumatic Brain Injury Model Systems at SCVMC with head computed tomography (CT) data. None. At discharge- length of stay, Functional Independence Measure (FIM), and Disability Rating Scale (DRS). One-year post-injury- Glasgow Outcome Scale (GOS), FIM, and Satisfaction with Life Scale (SWLS). Reults: Latent profile analysis (LPA) was used to identify subgroups with similar patterns across 12 indicators of injury severity, including duration of post-traumatic amnesia, Glasgow Coma Scale, time to follow commands, and head CT variables. LPA identified four latent classes: Class1 (least severe; N=75), Class2 (intermediate; N=124), Class3 (moderate; N=144), and Class4 (most severe; N=27). Younger age, lower education, rural residence, injury in motor vehicle accidents, and earlier injury years were associated with worse severity (ps