Preparation and characterization of nano-sized hydroxyapatite particles and hydroxyapatite/chitosan nano-composite for use in biomedical materials

Natural bone is actually an inorganic/organic composite mainly made up of nano-structure hydroxyapatite (Ca 10(PO 4) 6(OH) 2, HAp) and collagen fibers. It is of most importance to synthesize nano-composites of inorganic/organic in order to have good biocompatibility, high bioactivity and great bondi...

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Veröffentlicht in:	Materials letters 2002-12, Vol.57 (4), p.858-861
Hauptverfasser:	Chen, Fei, Wang, Zhou-Cheng, Lin, Chang-Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioinorganic chemistry Biological and medical sciences Chemistry Chitosan Composite Exact sciences and technology Fibers Hydroxyapatite Inorganic chemistry and origins of life Medical sciences Nano-sized Particles Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Technology. Biomaterials. Equipments
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Beschreibung
Zusammenfassung:	Natural bone is actually an inorganic/organic composite mainly made up of nano-structure hydroxyapatite (Ca 10(PO 4) 6(OH) 2, HAp) and collagen fibers. It is of most importance to synthesize nano-composites of inorganic/organic in order to have good biocompatibility, high bioactivity and great bonding properties. In this work, HAp nano-particle and HAp/chitosan (CTS) nano-composite with a homogeneous microstructure were prepared and characterized. It is proposed that the nano-structure of hydroxyapatite/chitosan composite will have the best biomedical properties in the biomaterials applications.
ISSN:	0167-577X 1873-4979
DOI:	10.1016/S0167-577X(02)00885-6