Chiral Silanols: Strategies and Tactics for Their Synthesis

Silanols are valuable and important compounds, which have found widespread applications in the field of materials science, synthetic chemistry, and medicinal chemistry. Although a handful of approaches have been developed for the synthesis of various silanols, access to enantioenriched silicon‐stereogenic silanols remains underdeveloped. This Concept article intends to summarize and highlight recent advances in the construction of silicon‐stereogenic silanols and endeavors to encourage further research in this area. Silanols, as the silicon analogues of alcohols, are valuable and important compounds, which have found widespread applications in the field of materials science, synthetic chemistry, and medicinal chemistry. This concept intends to highlight recent advances in the construction of silicon‐stereogenic silanols, and hope to inspire chemists to continue contributing to the development of novel synthetic methods toward chiral silanols.