Targeting ripening regulators to develop fruit with high quality and extended shelf life

Fruit quality directly impacts fruit marketability and consumer acceptance. Breeders have focused on fruit quality traits to extend shelf life, primarily through fruit texture, but, in some cases, have neglected other qualities such as flavor and nutrition. In recent years, integrative biotechnology and consumer-minded approaches have surfaced, aiding in the development of flavorful, long-lasting fruit. Here, we discussed how specific transcription factors and hormones involved in fruit ripening can be targeted to generate high-quality fruit through traditional breeding and bioengineering. We highlight regulators that can be used to generate novel-colored fruit or biofortify fresh produce with health-promoting nutrients, such as vitamin C. Overall, we argue that addressing grower and industry needs must be balanced with consumer-based traits. [Display omitted] •Fruit quality includes aspects of color, nutrition, flavor, texture, and shelf life.•Improving fruit quality can reduce food waste and increase nutritious food access.•Some consumer-based traits have declined with breeding longer shelf-life fruit.•Modulating ripening through breeding and biotechnology can improve fruit quality.