Efficacy and safety of basal insulin degludec 100 IU/mL versus glargine 300 IU/mL for type 1 diabetes: The single-center INEOX randomized controlled trial

•Deg-100 and Gla-300 had similar effect on HbA1c in adults with type 1 diabetes.•Basal insulin requirements were lower for Deg-100 than for Glar-300.•Higher incidence rate of hypoglycemia

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Bibliographische Detailangaben
Veröffentlicht in:	Diabetes research and clinical practice 2023-02, Vol.196, p.110238-110238, Article 110238
Hauptverfasser:	Ruiz de Adana, María Soledad, Domínguez, Marta Elena, Morillas, Virginia, Colomo, Natalia, Vallejo-Mora, Rosario, Guerrero, Mercedes, García-Escobar, Eva, Carreira, Mónica, Romero-Zerbo, Yanina, Linares, Francisca, González-Mariscal, Isabel, Bermúdez-Silva, Francisco Javier, Olveira, Gabriel, Rojo-Martínez, Gemma
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Blood Glucose - metabolism Clinical trial Degludec U-100 Diabetes Mellitus, Type 1 - drug therapy Glargine U-300 Glycated Hemoglobin Humans Hypoglycemia - drug therapy Hypoglycemic Agents - administration & dosage Insulin Glargine - administration & dosage Quality of Life Type 1 diabetes
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Beschreibung
Zusammenfassung:	•Deg-100 and Gla-300 had similar effect on HbA1c in adults with type 1 diabetes.•Basal insulin requirements were lower for Deg-100 than for Glar-300.•Higher incidence rate of hypoglycemia
ISSN:	0168-8227 1872-8227
DOI:	10.1016/j.diabres.2023.110238