Predicting the Risk of Type B Aortic Dissection Using Hemodynamic Parameters in Aortic Arches: A Comparative Study between Healthy and Repaired Aortas

•Both pathological anatomical features and hemodynamic indicators may be changed before the TBAD occur.•Hemodynamic indicators may be more accurate in predicting the risk and location of TBAD.•Averaged OSI and CFI index may be significantly enhanced in the region where the entry tears have appeared...

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Veröffentlicht in:Computer methods and programs in biomedicine 2023-03, Vol.230, p.107326-107326, Article 107326
Hauptverfasser: Wen, Jun, Huang, Haodi, Su, Zhiqiao, Jiang, Linke, Gao, Qi, Chen, Xiaoyi, Yan, Tingli, Peng, Liqing
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Sprache:eng
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Zusammenfassung:•Both pathological anatomical features and hemodynamic indicators may be changed before the TBAD occur.•Hemodynamic indicators may be more accurate in predicting the risk and location of TBAD.•Averaged OSI and CFI index may be significantly enhanced in the region where the entry tears have appeared before the TBAD occur.•As a new WSS-based indicator, TSVI was more sensitive to the marked tortuosity, which may have the potential to predict the risk of TBAD. The development of acute aortic dissection (AD) remains unpredictable due to the intricate nature of the AD mechanism and the varied patient-specific aortic anatomy. The aim of this study was to simulate the hemodynamic parameters in the aortas before the onset of TBAD with healthy controls. This study numerically assessed the effectiveness of hemodynamic indicators in predicting the risk of type B AD (TBAD) by investigating the differences in hemodynamic parameters between healthy and repaired aortas (aortas before TBAD development). Four wall shear stress (WSS)-based indicators and three helicity-based indicators were adopted and analyzed. The results showed that more pathological anatomical feathers can be observed in the repaired aortas. For WSS-based indicators, only averaged cross flow index (CFI) and oscillatory shear index OSI (CFI, 1.03 ± 0.07 vs. 0.83 ± 0.10 and OSI, 0.12 ± 0.03 vs. 0.04 ± 0.02) (all p
ISSN:0169-2607
1872-7565
DOI:10.1016/j.cmpb.2022.107326