Carbendazim: Ecological risks, toxicities, degradation pathways and potential risks to human health

Carbendazim is a highly effective benzimidazole fungicide and is widely used throughout the world. The effects of carbendazim contamination on the biology and environment should be paid more attention. We reviewed the published papers to evaluate the biological and environmental risks of carbendazim residues. The carbendazim has been frequently detected in the soil, water, air, and food samples and disrupted the soil and water ecosystem balances and functions. The carbendazim could induce embryonic, reproductive, developmental and hematological toxicities to different model animals. The carbendazim contamination can be remediated by photodegradation and chemical and microbial degradation. The carbendazim could enter into human body through food, drinking water and skin contact. Most of the existing studies were completed in the laboratory, and further studies should be conducted to reveal the effects of successive carbendazim applications in the field. [Display omitted] •Carbendazim can cause embryic, developmental, endocrine and hematological toxicities.•The long-term effects of carbendazim contamination should be concerned.•Combinations of different method have better removal efficiency of carbendazim.•Carbendazim could enter into human body via the food chain and skin contact.