Utilization of genetic testing in men with advanced prostate cancer

Background Genetic evaluation of men with advanced prostate cancer is recognized as imperative both to guide treatment decisions and to trigger cascade genetic testing of family members. Here we investigate utilization patterns of genetic testing among a contemporary cohort of men with advanced pros...

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Veröffentlicht in:The Prostate 2023-05, Vol.83 (6), p.516-523
Hauptverfasser: Aguiar, Jonathan A., Li, Eric V., Siddiqui, Mohammad R., Soliman, Moataz A., Kumar, Sai K. S. R., Schaeffer, Edward M., Keeter, Mary Kate, Brown, C. Hendricks, Szymaniak, Brittany M., Ross, Ashley E.
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Sprache:eng
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Zusammenfassung:Background Genetic evaluation of men with advanced prostate cancer is recognized as imperative both to guide treatment decisions and to trigger cascade genetic testing of family members. Here we investigate utilization patterns of genetic testing among a contemporary cohort of men with advanced prostate cancer at our institution. Methods We queried the Northwestern Electronic Data Warehouse from January 2021 to present for all men diagnosed with National Comprehensive Cancer Network high‐risk/very high‐risk, regional, or metastatic prostate cancer. Patients were excluded from analyses if treated at an outside institution and/or presented for a second opinion evaluation. Statistics were performed using t‐test, Chi‐squared test, and univariable and multivariable logistic regression with significance defined as p 
ISSN:0270-4137
1097-0045
DOI:10.1002/pros.24480