Trajectory of serum chloride levels during decongestive therapy in acute heart failure

Hypochloremia is a risk factor for poor outcomes in patients with acute heart failure (AHF). However, the changes in serum chloride levels during decongestion therapy and their impact on prognosis remain unknown. In total, 2798 patients with AHF were retrospectively studied and divided into four gro...

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Veröffentlicht in:International journal of cardiology 2023-03, Vol.375, p.36-43
Hauptverfasser: Kurashima, Shinichi, Kitai, Takeshi, Matsue, Yuya, Nogi, Kazutaka, Kagiyama, Nobuyuki, Oishi, Shogo, Akiyama, Eiichi, Suzuki, Satoshi, Yamamoto, Masayoshi, Kida, Keisuke, Okumura, Takahiro, Nogi, Maki, Ishihara, Satomi, Ueda, Tomoya, Kawakami, Rika, Furukawa, Yutaka, Saito, Yoshihiko, Izumi, Chisato
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Sprache:eng
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Zusammenfassung:Hypochloremia is a risk factor for poor outcomes in patients with acute heart failure (AHF). However, the changes in serum chloride levels during decongestion therapy and their impact on prognosis remain unknown. In total, 2798 patients with AHF were retrospectively studied and divided into four groups according to their admission and discharge serum chloride levels: (1) normochloremia (n=2,192, 78%); (2) treatment-associated hypochloremia, defined as admission normochloremia with a subsequent decrease (
ISSN:0167-5273
1874-1754
DOI:10.1016/j.ijcard.2022.12.041