Prognostic significance of head and neck spindle cell carcinoma

Prognostic significance of head and neck spindle cell carcinoma

Background Our study investigates the prognostic significance of spindle cell histology on overall survival (OS) of conventional head and neck squamous cell carcinoma (HNSCC). Methods The 2004 to 2017 National Cancer Database was queried for patients with head and neck spindle cell carcinoma (HNSpCC...

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Veröffentlicht in:Head & neck 2023-03, Vol.45 (3), p.685-696
Hauptverfasser: Patel, Aman M., Choudhry, Hannaan S., Desai, Amar D., Shah, Vraj P., Patel, Prayag, Eloy, Jean Anderson, Roden, Dylan F., Fang, Christina H.
Format: Artikel
Sprache:eng
Schlagworte:
Cancer
Carcinoma, Squamous Cell - pathology
Cell survival
Head & neck cancer
Head and neck carcinoma
Head and Neck Neoplasms - therapy
Histology
Humans
Hypopharynx
Larynx
National Cancer Database
Oral cavity
Oropharynx
overall survival
primary site
Prognosis
Salivary gland
spindle cell
squamous cell
Squamous cell carcinoma
Squamous Cell Carcinoma of Head and Neck - therapy
Tumors
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Zusammenfassung:Background Our study investigates the prognostic significance of spindle cell histology on overall survival (OS) of conventional head and neck squamous cell carcinoma (HNSCC). Methods The 2004 to 2017 National Cancer Database was queried for patients with head and neck spindle cell carcinoma (HNSpCC) (n = 1572) or HNSCC (n = 242 697) of the oral cavity, major salivary glands, sinonasal tract, oropharynx, hypopharynx, and larynx treated with curative intent. Results Patients with HNSpCC presented more frequently with higher‐grade tumors and cN0 disease than those with HNSCC (p 
ISSN:1043-3074
1097-0347
DOI:10.1002/hed.27285