Human assumed central sensitization in people with acute non‐specific low back pain: A cross‐sectional study of the association with brain‐derived neurotrophic factor, clinical, psychological and demographic factors

Human assumed central sensitization in people with acute non‐specific low back pain: A cross‐sectional study of the association with brain‐derived neurotrophic factor, clinical, psychological and demographic factors

Background Early evidence suggests human assumed central sensitization (HACS) is present in some people with acute low back pain (LBP). Factors influencing individual variation in HACS during acute LBP have not been fully explored. We aimed to examine the evidence for HACS in acute LBP and the contr...

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Veröffentlicht in:European journal of pain 2023-04, Vol.27 (4), p.530-545
Hauptverfasser: Chang, Wei‐Ju, Jenkins, Luke C., Humburg, Peter, Schabrun, Siobhan M.
Format: Artikel
Sprache:eng
Schlagworte:
Acute Pain - psychology
Brain-Derived Neurotrophic Factor
Central Nervous System Sensitization
Cross-Sectional Studies
Demography
Humans
Low Back Pain - psychology
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Zusammenfassung:Background Early evidence suggests human assumed central sensitization (HACS) is present in some people with acute low back pain (LBP). Factors influencing individual variation in HACS during acute LBP have not been fully explored. We aimed to examine the evidence for HACS in acute LBP and the contribution of brain‐derived neurotrophic factor (BDNF), clinical, psychological and demographic factors to HACS. Methods Participants with acute LBP (
ISSN:1090-3801
1532-2149
DOI:10.1002/ejp.2078