Tracing weak neuron fibers

Tracing weak neuron fibers

Abstract Motivation Precise reconstruction of neuronal arbors is important for circuitry mapping. Many auto-tracing algorithms have been developed toward full reconstruction. However, it is still challenging to trace the weak signals of neurite fibers that often correspond to axons. Results We propo...

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Veröffentlicht in:Bioinformatics (Oxford, England) England), 2023-01, Vol.39 (1)
Hauptverfasser: Liu, Yufeng, Zhong, Ye, Zhao, Xuan, Liu, Lijuan, Ding, Liya, Peng, Hanchuan
Format: Artikel
Sprache:eng
Schlagworte:
Algorithms
Animals
Availability
Axons
Bioinformatics
Brain
Circuits
Fibers
Image resolution
Mice
Neurites
Neuroimaging
Neurons
Reconstruction
Software
Tracing
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Zusammenfassung:Abstract Motivation Precise reconstruction of neuronal arbors is important for circuitry mapping. Many auto-tracing algorithms have been developed toward full reconstruction. However, it is still challenging to trace the weak signals of neurite fibers that often correspond to axons. Results We proposed a method, named the NeuMiner, for tracing weak fibers by combining two strategies: an online sample mining strategy and a modified gamma transformation. NeuMiner improved the recall of weak signals (voxel values
ISSN:1367-4803
1367-4811
DOI:10.1093/bioinformatics/btac816