Multiple metastases of clear cell sarcoma at diagnosis presented in bone marrow aspirate: A case report

Clear cell sarcoma (CCS) is a rare and aggressive soft‐tissue sarcoma that arises most commonly in adolescents and young adults of both sexes. CCS presents a diagnostic challenge due to its morphological and immunohistochemical similarity to malignant melanoma. We present a rare and severe case of CCS simultaneously with multiple bone and lymph node metastases at the time of initial diagnosis in a previously healthy 15‐year‐old Chinese man. Detailed information on clinical manifestations, laboratory profiles, histopathological findings and poor outcome were described. The cytomorphology of bone marrow aspirate in CCS in Wright–Giemsa staining smear was first depicted in this case. The diagnostic difficulties of the rare case was also discussed.